Tuesday, 18 March 2014

Isothermal Nucleic Acid Amplification Technologies (INAAT) Market is expected to reach $1.6 Billion by 2017

INTRODUCTION:
Isothermal amplification of Nucleic acid or DNA is carried out at steady temperatures as the term ‘Isothermal’ obviates the need for thermal cyclers. Nucleic acid amplification technologies are used as leading methods in detecting and analyzing nucleic acids. These are the emerging DNA technologies in the field of molecular biology. Nucleic Acid Testing promises rapid, sensitive and specific diagnosis of infectious, inherited and genetic diseases.

NEED FOR ISOTHERMAL AMPLIFICATION TECHNOLOGIES:
Amplification of nucleic acids or DNA helps in detection and identification of infectious diseases, genetic disorders and other research purposes. The most widely used amplification technology is the Polumerase chain reaction (PCR) but as it requires a thermocycling machine to separate two DNA strands and then amplify the required fragment, the possibility of amplifying DNA in isothermal conditions is considered. DNA polymerase replicates DNA with the aid of various accessory proteins. Recent identification of these proteins has enabled development of new in vitro isothermal DNA amplification methods, mimicking these in vivo mechanisms.

Types  of isothermal nucleic acid amplification methods:
1.       Transcription mediated amplification.
2.       Nucleic acid sequence-based amplification.
3.       Signal mediated amplification of RNA technology.
4.       Strand displacement amplification.
5.       Rolling circle amplification.
6.       Loop-mediated isothermal amplification of DNA.
7.       Isothermal multiple displacement amplification.
8.       Helicase-dependent amplification.
9.       Single primer isothermal amplification.
10.   Circular helicase-dependent amplification.

CURRENT SCENARIO OF INAAT MARKET:
According to a new market research report by MarketsandMarkets, the global Isothermal nucleic acid amplification technologies (INAAT) market has been valued over a billion at a CAGR of 17% and is expected to reach $1.6 billion by 2017. The Isothermal Nucleic Acid Amplification Technologies Market report would provide an in-depth analysis of the global INAAT market, its applications, key trends and drivers, assessment of technological advancements, investment potential, market size and forecasts by 2017. It also provides a comprehensive picture of various types of INAAT platforms like LAMP (loop-mediated isothermal amplification), NASBA (nucleic acid sequence based amplification), TMA (transcription mediated amplification), SPIA (single primer isothermal amplification), SDA (strand displacement amplification), and HDA (helicase dependent amplification).




                                      Source: http://www.marketsandmarkets.com/

FUTURE PROSPECTS:

There are numerous factors which are prompting the growth of INAAT market such as high incidence of infectious disease, pandemic threats, and emergence of new infections. Hence this market is primarily driven due to high demands of the industry and end users. There have been lots of investment activities over the past two decades, directed towards research and development of these technologies, attracting interests industry firms and academic institutes. New developments such as digital INAAT devices, chip based amplification, multiplexing and detection of pathogens using fluorescent detection systems are the emerging trends in INAAT market. The next promising players in the INAAT market are China, India, South Africa and other regions of Asia pacific, Africa and untapped markets of Europe. The Key Players in this market are Hologic-Gen-Probe, bioMerieux, BD Diagnostics, Qiagen, Alere, Eiken Chemical, Meridian Bioscience, BioHelix and Quidel.

The report can be referred here:
http://www.prweb.com/releases/isothermal-nucleic-acid/technologies-inaat-market/prweb10352286.htm

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