The term ‘Chromatography’ is referred to a broad range of
physical methods which are used to separate mixtures. The separation is done
with the help of two phases namely, stationary phase and mobile phase. The mobile
phase is basically a fluid in which the mixture is dissolved. The mobile phase carries
the mixture through the stationary phase. The various constituents of the
mixture get separated as they travel at different speeds. Hence the reagents
needed for carrying out chromatography should be chosen accurately. Chromatography may be preparative or analytical. Preparative chromatography
is used to separate the components of a mixture for more advanced use whereas analytical
chromatography is done normally with smaller amounts of material and is for
measuring the relative proportions of analytes in a mixture. Preparative and
analytical chromatographies are not mutually exclusive.
Chromatography is very special taken the need to
separate a product from a complex mixture into consideration. Hence it is a
very important step in the production line of any chemical industry. Chromatography
can separate complex mixtures with great precision. Even very complex
components, such as proteins that may only vary by a single amino acid,
can be separated with chromatography. Secondly, chromatography can also be used
to separate delicate products since the conditions under which it is performed
are not typically severe. Other major factors driving the chromatography
reagents market are:
1.
Rise in government investments.
2.
Increasing demand of chromatography reagents
in the pharmaceutical industry.
3.
Innovation in market.
4.
Incessant rise in acquisitions/partnerships
among players in the market.
5.
Rampant usage of chromatography reagents.
Source: http://www.intechopen.com/
Types
of chromatography:
1.
Gas
chromatography: It is used for volatile compounds. The mobile phase is a gas and the
stationary phase is usually a liquid on a solid support or absorbent.
2.
High-performance liquid
chromatography (HPLC): Utilizes
high-pressure pumps to increase the efficiency of the separation.
3.
Liquid chromatography: Applied to separate analytes in
solutions. The mobile phase is a solvent and the stationary phase is a liquid
on a solid support, a solid, or an ion-exchange resin.
4.
Size-Exclusion
chromatography: The mobile phase is a solvent
& the stationary phase is a porous particles package.
5.
Thin-layer
chromatography: The
mobile phase is a solvent and the stationary phase is a solid adsorbent on a
thin flat support.
According to a new market research report, the global chromatography reagents market is estimated
at $4,598.0 million in 2013 and is expected to grow at a CAGR of 10.6% from
2013 to 2018, to reach $7,609.3 million by 2018. The report
categorizes the global chromatography Reagents Market categories by Type
[Acylation, Alkylation, Solvent, Buffer], Bed Shape [Column, Thin layer],
Mobile Phase [UHPLC, HPLC, HILIC, Flash, SFC], Separation Mechanism [Partition,
Adsorption, Affinity] & End User and by Geography.
The report can be referred here:
http://www.prweb.com/releases/chromatography-reagents/market/prweb11034806.htm
http://www.prweb.com/releases/chromatography-reagents/market/prweb11034806.htm
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